Under the Portuguese Presidency of the Council of the European Union in the first half of 2021, this 2021 edition of the EuroNanoForum addressed, during the two days of the conference (5-6 May 2021), Nanotechnology and Advanced Materials as the key elements to guarantee the functioning, long term durability, safety, and environmental compatibility of many devices, machinery, and services, highlighting the fundamental role of advanced materials for the transition to greener technologies, and a more sustainable future, making a significant contribution to the ambitious goals set by the European Green Deal. Furthermore, the role of nano-enabled industries in the drive towards a green and resilient Europe was also enhanced.